必威体育登录手机Agilent Technologies Thought Leader Award Supports Dr.Joshua Rabinowitz's Research at Princeton University
Team Developing LC/MS Methods, Bioinformatics Tools for Discovery of Metabolic Regulatory Mechanisms
SANTA CLARA, Calif., April 17, 2014
必威体育登录手机Agilent Technologies Inc.(NYSE: A) today announced thatJoshua Rabinowitz, M.D, Ph.D., professor at Princeton University's Department of Chemistry and theLewis-Sigler Institute for Integrative Genomics必威体育登录手机, has received an Agilent Thought Leader Award to support his work on quantitative analysis of cellular metabolism.
Dr.Rabinowitz is a world-renowned scientist who has made seminal conceptual and methodological contributions to the metabolomics field.These include the development of isotopic labeling, sample preparation, data analysis, and information visualization techniques for liquid chromatography/mass spectrometry data.Together these techniques allow researchers to piece together static snapshots of metabolite levels provided by LC/MS into an understanding of dynamic metabolic activity in living systems.Dr.Rabinowitz has applied these tools to identify metabolic remodeling in infectious disease and cancer pathogenesis.The resulting understanding has led to new targets for therapeutic intervention.
"We are very happy to expand our work with Dr.必威体育登录手机Rabinowitz and his team to support their efforts developing quantitative proteomics methodologies and pan-omics studies of metabolism," said John Fjeldsted, Agilent's director of Mass Spectrometry Research and Development."We believe this work will have a significant impact in many fundamental areas of research."
必威体育登录手机The Agilent award will support Dr.Rabinowitz's research on global cell metabolism and its regulation.必威体育登录手机He will make use of the quantitative capabilities of the Agilent 6550 MS-QTOF to generate protein stability information to supplement transcriptomics, proteomics, metabolomics, and metabolic flux data sets.From protein abundances and stabilities, he will be able to infer protein fluxes and thereby assemble an integrative understanding of how protein levels are regulated and how this ties into overall cellular metabolic activity.
必威体育登录手机"I am delighted to be working with Agilent, whose combined expertise in wet chemistry, instrumentation and software makes them an outstanding partner for my lab," said Dr.Rabinowitz.必威体育登录手机"We share Agilent's goal of enabling quantitative measurement of all key biomolecules, and of building computational tools that integrate such data to reveal new principles of living systems.Such tools hold the potential to revolutionize biomedical research."
必威体育登录手机The Agilent Thought Leader Award promotes fundamental scientific advances by contributing financial support, products and expertise to the research of influential thought leaders in life sciences and chemical analysis.必威体育登录手机Information about previous award recipients is available at Agilent'sThought Leader Program website.
The Lewis-Sigler Institute for Integrative Genomics
The Lewis-Sigler Institute for Integrative Genomics, housed in the Carl Icahn Laboratory at Princeton University, was established to innovate in research and teaching at the interface of modern biology and the more quantitative sciences.The Institute is the hub of theCenter for Quantitative Biology, funded by the National Institute of General Medical Sciences, one branch of the National Institutes of Health.
必威体育登录手机About Agilent Technologies
必威体育登录手机Agilent Technologies Inc.(NYSE: A) is the world's premier measurement company and a technology leader in chemical analysis, life sciences, diagnostics, electronics and communications.The company's 20,600 employees serve customers in more than 100 countries.必威体育登录手机Agilent had revenues of $6.8 billion in fiscal 2013.必威体育登录手机Information about Agilent is available at必威体育登录手机www.dayu-jc.com.
On Sept.必威体育登录手机19, 2013, Agilent announced plans to separate into two publicly traded companies through a tax-free spinoff of its electronic measurement business.The new company is named Keysight Technologies, Inc.The separation is expected to be completed in early November 2014.
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