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必威体育登录手机This application note demonstrates the feasibility and use of combining multiple cell-based in vitro assays from Agilent that use diverse analytical technologies to investigate the cardiac liability of drugs.
This application note describes pulse labeling methods based on inorganic quantum dots, organic nanoparticles, dyes that covalently modify cytoplasmic proteins, and baculovirus.After evaluating each reagent's labeling efficiency across a population...
This app note demonstrates the feasibility of using a connected workflow to evaluate the effect of inotropic compounds on electrically paced human iPSC derived cardiomyocytes (hiPSC-CMs) through calcium imaging
必威体育登录手机Describes use of a tethering approach to immobilize liquid tumor cell lines on to the surface of gold biosensors embedded in an Agilent E-Plate.
必威体育登录手机The Agilent xCELLigence RTCA eSight monitors 3D tumor spheroid growth/shrinkage in real time using brightfield plus red, green, and blue fluorescence.
必威体育登录手机This study used the Agilent xCELLigence RTCA CardioECR system with human iPSC-derived cardiomyocytes (hiPSC-CMs) to evaluate cardiac safety/toxicity of antiviral drugs.
必威体育登录手机A demonstration of the use of the Agilent xCELLigence RTCA CardioECR system to compare functional profiles of contractility and electrophysiology between an PS-iPSC-CM disease model and its isogenic control.
Noninvasive and continuous monitoring of the perturbation of cellular growth following exposure to the cumulative toxicants present in water samples.
必威体育登录手机A demonstration of how the Agilent xCELLigence RTCA eSight real-time imaging platform can be used to monitor phagocytosis, using a model system comprising macrophages and E.coli cells conjugated to a pH-sensitive fluorescent dye.
必威体育登录手机A demonstration of how the Agilent xCELLigence RTCA eSight real-time imaging platform can be used to monitor induction of the unfolded protein response using a genetically encoded fluorescent sensor.
必威体育登录手机A demonstration of how the Agilent xCELLigence RTCA eSight can be used to identify and characterize virus neutralizing antibodies in real-time
A demonstration of how the eSight combines the strengths of real-time impedance monitoring with those of live cell imaging, to increase the information richness of your proliferation assays while simultaneously reducing the workload.
In this application note, a series of experiments demonstrate how the xCELLigence RTCA system can be applied to quantitatively monitor NK cell‑mediated cytolysis without labeling the target cells.
This application note describes the experimental setup for assessing vesicular stomatitis virus-mediated cytotoxicity of Vero E6 cells and HEK 293 cells using an xCELLigence instrument.
This application note demonstrates how the xCELLigence system can run GPCR assays without expressing additional reporter proteins.
In this application note, a series of experiments is described to demonstrate that the xCELLigence system is suitable for monitoring cell adhesion and spreading.
To determine if the stimulation of endogenously expressed GPCRs can be monitored by the xCELLigence system, cells were stimulated with various receptor agonists, triggering either Gs-, Gi-, or Gq-mediated downstream signals.
This application note highlights the development and utility of an alternative receptor tyrosine kinase assay that uses the impedance‑based xCELLigence system.
In this application note, a series of experiments demonstrates how the xCELLigence system may be used to monitor functional activation of GPCRs in living cells.
In this application note, the RTCA Cardio instrument is used with human stem cell-derived cardiomyocytes (iCell Cardiomyocytes) for assessment of the cardiac safety profile of leading compounds or drug candidates during drug development.