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Application note for MS of AAV CQAs
- Publication Part Number: 5994-5110EN
- Created: 14 July 2022
- 698 KB
必威体育登录手机This application note demonstrates an oligonucleotide sequence confirmation workflow using Agilent BioConfirm software with an Agilent 1290 Infinity II LC and Agilent 6545XT AdvanceBio LC/Q-TOF.
- Publication Part Number: 5994-5071EN
- Created: 13 July 2022
- 2 MB
This application note describes the characterization of product‑related impurities in the development of new oligonucleotide biotherapeutics using LC/(Q)-TOF and MassHunter BioConfirm software.
- Publication Part Number: 5994-4817EN
- Created: 13 May 2022
- 2 MB
This application note describes common method parameters that can be optimized when purifying oligonucleotides ranging from 25 to 100 bases in length.
- Publication Part Number: 5994-4753EN
- Created: 01 Apr 2022
- 416 KB
必威体育登录手机Analysis of Full/Empty Capsid Ratios in AAV 1 and 6 Serotypes using the Agilent 1290 Infinity II Bio LC with Agilent Bio SAX strong anion exchange columns
- Publication Part Number: 5994-4589EN
- Created: 18 Feb 2022
- 812 KB
A method for analyzing primary amino acids in cell culture media using AdvanceBio Amino Acid Analysis (AAA) solution with absorbance detection
- Publication Part Number: 5991-7922EN
- Created: 16 Nov 2021
- 736 KB
Application compendium for glycan analysis.
- Publication Part Number: 5994-0035EN
- Created: 15 Nov 2021
- 7 MB
Aggregate and Fragment Analysis of Adeno-Associated Viral Vectors using Size Exlusion is a critical analysis.Bio SEC-5 demonstrates reproducible separation and resolution of these AAV particles and aggregates.
- Publication Part Number: 5994-4270EN
- Created: 27 Oct 2021
- 454 KB
Critical Quality Attributes Titer Determination compendium
- Publication Part Number: 5994-0038EN
- Created: 30 Sep 2021
- 2 MB
Virus-like particles (VLPs) are highly structured protein particles that are self-assembled from one or more structural proteins, typically 20 to 150 nm in diameter.
- Publication Part Number: 5994-4227EN
- Created: 29 Sep 2021
- 194 KB
必威体育登录手机Rapid mRNA capping analysis with a combined sample preparation and analysis time of only 75 minutes using an Agilent 6545XT AdvanceBio LC/Q-TOF.
- Publication Part Number: 5994-3984EN
- Created: 21 Sep 2021
- 1 MB
必威体育登录手机Streamlined workflows for N-Glycan analysis of biotherapeutics using Agilent AdvanceBio Gly-X InstantPC and 2-AB Express sample preparation with LC/FLD/MS
- Publication Part Number: 5994-1348EN
- Created: 21 Sep 2021
- 1 MB
This application note tests the recombinant protein A column at the maximum flow rate and performs the bridging study against the native protein A column.
- Publication Part Number: 5994-3969EN
- Created: 18 Aug 2021
- 744 KB
必威体育登录手机Agilent Bio-Monolith Protein G quantitates supernatant mAbs across a wide loading range at many flow rates, complementing Protein A for fast titer analysis.
- Publication Part Number: 5991-6094EN
- Created: 16 June 2021
- 683 KB
Application note for the rapid analysis of adenoviruse type 5 particles with bio-monolith anion-exchange HPLC Columns
- Publication Part Number: 5990-5524EN
- Created: 26 May 2021
- 571 KB
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必威体育登录手机An SEC method identifying innovator and biosimilar insulin analog was developed using an Agilent AdvanceBio SEC 130Å, 7.8 × 300 mm, 2.7 μm column.
- Publication Part Number: 5991-6872EN
- Created: 12 May 2021
- 513 KB
Evaluation of SEC Columns for Analysis of ADC Aggregates and Fragments - Choosing the best stationary phase to overcome nonspecific interactions.
- Publication Part Number: 5994-3276EN
- Created: 11 May 2021
- 376 KB
This application note demonstrates the purification workflow of a single-stranded RNA ON by ion-pair reversed-phase HPLC.
- Publication Part Number: 5994-3514EN
- Created: 06 May 2021
- 365 KB
必威体育登录手机This collection of Agilent app notes on amino acid analysis also includes our guide on how to get accurate results with an AdvanceBio end-to-end solution.
- Publication Part Number: 5994-0033EN
- Created: 30 Apr 2021
- 4 MB
Critical Quality Attributes Peptide Mapping compendium
- Publication Part Number: 5994-0037EN
- Created: 23 Apr 2021
- 10 MB