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This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
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Fraction collection for metabolite enrichment, biphasic solvent extraction, orthogonal column chemistries, and LC/MS and GC/MS detection, lead to greater metabolite coverage.
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必威体育登录手机The Agilent AdvanceBio Peptide Mapping column separates mAb tryptic digests at low system pressures, providing UHPLC performance from HPLC operating conditions.
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Peptide mapping is the common analytical technique for characterizing biologic therapeutic proteins.
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| Chinese (Simplified) (China) | Complete (PDF) |
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