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Biopharma HPLC Analysis (6)
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Intact Protein Analysis (9)
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LC (8)
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Bio SEC-3 (2)
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Example category image description
Applications
必威体育登录手机Detailed Aggregation Characterization of Monoclonal Antibodies Using the Agilent 1260 Infinity Multi-Detector Bio-SEC Solution with Advanced Light Scattering Detection (PDF)

必威体育登录手机This Application Note shows detailed size exclusion analysis of monoclonal antibodies and their aggregates using the Agilent 1260 Infinity Multi-Detector Bio-

  • Publication Part Number: 5991-3954EN
  • Created: 01 May 2016
  • 1 MB
  • PDF
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Publication Part Number 5991-3954EN
Analysis Analysed with Part No.
Bio SEC-3
Instrument
必威体育登录手机Agilent 1260 Infinity
Analytical Technique Technique
LC
SEC
Injection
valve
Detection
DAD
LSD
Sample Chemical Group
monoclonal antibodies
示例矩陣
test mixture
Example category image description
Applications
必威体育登录手机Analysis of Monoclonal Antibody (mAb) Using Agilent 1290 Infinity LC System Coupled to Agilent 6530 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) (PDF)

This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.

  • Publication Part Number: 5991-4266EN
  • Created: 01 July 2014
  • 310 KB
  • PDF
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Publication Part Number 5991-4266EN
Analysis Analysed with Part No.
Poroshell 300SB-C8
Instrument
必威体育登录手机Agilent 1290 Infinity
必威体育登录手机Agilent 6530
Analytical Technique Technique
LC
Injection
valve
Detection
MS-QTOF
Sample Chemical Group
monoclonal antibodies
示例矩陣
test mixture
Example category image description
Applications
必威体育登录手机Analysis of Intact and C-terminal Digested IgG1 on an Agilent Bio MAb NP5 Column (PDF)

必威体育登录手机Agilent Bio MAb columns, in an Agilent 1260 Infinity Bio-inert Quaternary LC, characterize the charge heterogeneity of IgG1monoclonal antibody...

  • Publication Part Number: 5991-0895EN
  • Created: 01 Aug 2013
  • 240 KB
  • PDF
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Publication Part Number 5991-0895EN
Analysis Analysed with Part No.
Bio Mab NP 5
Instrument
必威体育登录手机Agilent 1100
必威体育登录手机Agilent 1260 Infinity
Analytical Technique Technique
LC
Injection
valve
Detection
UV
Sample Chemical Group
bio-therapeutics
monoclonal antibodies
示例矩陣
chinese hamster
Chinese (Simplified) (China) Complete (PDF)
Example category image description
Applications
pH Gradient Elution for Improved Separation of Monoclonal Antibody Charge Variants (PDF)

Ion exchange is a very useful technique to separate protein mixtures under mild conditions, most commonly by applying a shallow gradient of increasing salt concentration as el

  • Publication Part Number: 5990-9629EN
  • Created: 01 Aug 2013
  • 1 MB
  • PDF
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Publication Part Number 5990-9629EN
Analysis Analysed with Part No.
Bio Mab NP 5
Instrument
必威体育登录手机Agilent 1260 Infinity
Analytical Technique Technique
LC
Injection
valve
Detection
UV
Sample Chemical Group
monoclonal antibodies
proteins
示例矩陣
test mixture
Chinese (Simplified) (China) Complete (PDF)
Example category image description
Applications
必威体育登录手机Disulfide Linkage Analysis of IgG1 using an Agilent 1260 Infinity Bio-inert LC System with an Agilent ZORBAX RRHD Diphenyl sub-2 μm Column (PDF)

This Application Note describes a simple method for the analysis of disulfide linkages in monoclonal antibodies (mAbs) by reversed phase HPLC.

  • Publication Part Number: 5991-1694EN
  • Created: 01 Feb 2013
  • 899 KB
  • PDF
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Publication Part Number 5991-1694EN
Analysis Analysed with Part No.
ZORBAX RRHD 300-DP
Instrument
必威体育登录手机Agilent 1260 Infinity
Analytical Technique Technique
LC
Injection
valve
Detection
DAD
Sample Chemical Group
monoclonal antibodies
示例矩陣
test mixture
Chinese (Simplified) (China) Complete (PDF)
Example category image description
Applications
必威体育登录手机Reversed-Phase Optimization for Ultra Fast Profiling of Intact and Reduced Monoclonal Antibodies using Agilent ZORBAX Rapid Resolution High Definition 300SB-C3 Column (PDF)

必威体育登录手机Rapid reversed-phase separations of intact and reduced monoclonal antibodies (mAbs) were optimized using Agilent ZORBAX RRHD 300SB-C3 columns.

  • Publication Part Number: 5990-9667EN
  • Created: 13 Feb 2012
  • 364 KB
  • PDF
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Publication Part Number 5990-9667EN
Analysis Analysed with Part No.
ZORBAX 300SB-C3
Instrument
必威体育登录手机Agilent 1290 Infinity
Analytical Technique Technique
LC
Injection
valve
Detection
UV
Sample Chemical Group
monoclonal antibodies
proteins
示例矩陣
test mixture
Chinese (Simplified) (China) Complete (PDF)
Example category image description
Applications
必威体育登录手机Ultra High Speed and High Resolution Separations of Reduced and Intact Monoclonal Antibodies with Agilent ZORBAX RRHD Sub-2 μm 300 Diphenyl UHPLC Column (PDF)

JM

  • Publication Part Number: 5990-9668EN
  • Created: 07 Feb 2012
  • 807 KB
  • PDF
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Publication Part Number 5990-9668EN
Analysis Analysed with Part No.
ZORBAX 300-Diphenyl
ZORBAX RRHD 300-DP
Instrument
必威体育登录手机Agilent 1290 Infinity
Analytical Technique Technique
LC
Injection
valve
Detection
UV
Sample Chemical Group
monoclonal antibodies
proteins
示例矩陣
chinese hamster ovary
test mixture
Chinese (Simplified) (China) Complete (PDF)
Example category image description
Applications
必威体育登录手机Rapid UHPLC Analysis of Reduced Monoclonal Antibodies using an Agilent ZORBAX Rapid Resolution High Definition (RRHD) 300SB-C8 Column (PDF)

必威体育登录手机An Agilent ZORBAX sub-2 RRHD 300SB-C8 reversed-phase column was used to deliver highly resolved ultra fast separations of reduced and akylated monoclonal antibodies.

  • Publication Part Number: 5990-9631EN
  • Created: 17 Jan 2012
  • 664 KB
  • PDF
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Publication Part Number 5990-9631EN
Analysis Analysed with Part No.
ZORBAX RRHD 300 SB-C8
Instrument
必威体育登录手机Agilent 1290 Infinity
Analytical Technique Technique
LC/MS
UHPLC
Injection
valve
Detection
DAD
LC/MS/MS
Sample Chemical Group
monoclonal antibodies
示例矩陣
test mixture
Chinese (Simplified) (China) Complete (PDF)
Example category image description
Applications
必威体育登录手机Characterization of monoclonal antibodies on the Agilent 1260 Infinity Bio-inert Quaternary LC by Size Exclusion Chromatography using the Agilent BioSEC columns (PDF)

必威体育登录手机Application note for the characterization of monoclonal antibodies on the Agilent 1260 Infinity Bio-inert Quaternary LC by SEC using the Agilent BioSEC columns

  • Publication Part Number: 5990-6414EN
  • Created: 01 Feb 2011
  • 996 KB
  • PDF
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Publication Part Number 5990-6414EN
Analysis Analysed with Part No.
Bio SEC-3
Bio SEC-5
Instrument
必威体育登录手机Agilent 1200
必威体育登录手机Agilent 1260 Infinity
Analytical Technique Technique
GPC
LC
SEC
Injection
valve
Detection
DAD
Sample Chemical Group
antibodies
monoclonal antibodies
示例矩陣
test mixture

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