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Clone selection is important during Monoclonal antibodies development.Proof of principle using 2D-LC/MS solution is demonstrated for identifying the correct clone.
| Korean (Korea) | Complete (PDF) |
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必威体育登录手机Agilent PLRP-S column demonstrates superior separation performance for the analysis of mAbs and ADC at both intact and fragment levels
必威体育登录手机Agilent AssayMAP Bravo platform automates a wide variety of LC/MS sample prep workflows on a single instrument including simultaneous processing of 8–96 samples.
In this paper, we are investigating an antibody drug conjugate (ADC) with a cysteine linker.
Using Microfluidic HPLC-Chip/MS
| Chinese (Simplified) (China) | Complete (PDF) |
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Using Automated Sample Preparation and LC/MS Analysis
| Chinese (Simplified) (China) | Complete (PDF) |
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Determination of DAR for intact and reduced lysine conjugated ADCs using liquid chromatography/mass spectrometry and easy-to-use data analysis software.
| Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机Intact and reduced ADCs were processed using AssayMAP Bravo platform, and analyzed using the Agilent LC/MS.必威体育登录手机The DAR was determined with the Agilent DAR calculator.
| Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机Agilent AssayMAP Bravo automates the sample preparation for isolating surface membrane proteins in high-throughput fashion.
High sensitivity and effective interference reduction for multiple sulfur isotopes, allows accurate determination of sulfur in biological molecules using IDMS
This Application Note demonstrates the utility of capillary electrophoresis/mass spectrometry (CE/MS) for the analysis of intact monoclonal antibodies.
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
| Publication Part Number | 5991-4266EN | ||
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Antibody conjugates are of significant interest in biopharma industry as therapeutic agents.This note demonstrates the use of the CE/MS analysis for immunoconjugates.
必威体育登录手机Application note for Agilent Infinity Series/LC Columns Pharmaceutical Compendium
New peak modeling deconvolution (pMod) algorithm provides results with less artifacts, precise zero-charge mass measurement, and enhanced resolution of protein peaks
| Chinese (Simplified) (China) | Complete (PDF) |
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A comparison of the separation and sequence coverage of glycoproteins by reversed-phase and HILIC demonstrates the utility of HILIC.
| Publication Part Number | 5991-2085EN | ||||
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| Korean (Korea) | Complete (PDF) |
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Fast and efficient LC TOF/MS characterizes intact and digested IgG to identify glycoform masses and profiles.mAb-glyco chip analysis built a glycan accurate mass database.
| Publication Part Number | 5990-2323EN | ||||
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Calibration of the ZORBAX GF-250 Column with Globular Proteins, ZORBAX GF-250, 884973-901, Lab Insight, TE4
Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
| Publication Part Number | 5991-2116EN | |||
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