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Presents the use of AdvanceBio Desalting-RP cartridges to pretreat mAb and ADC samples before MS analysis.
必威体育登录手机An Agilent AdvanceBio MS Spent Media column is used to separate saccharide and sialic acid USP standards, with an Agilent 1260 Infinity II LC and TOF MS detection.
| Japanese (Japan) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
必威体育登录手机An Agilent LC system, ZORBAX column and optimized LC gradient were used for fast separation of blood plasma lipids with 15 minutes cycle time injection-to injection.
This study demonstrates an HCP analysis workflow
| Japanese (Japan) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.
| Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机This application note evaluates the performance of an Agilent LC/MS in terms of achievable mass accuracy and spectral accuracy to enable unknown formula ID.
A high performance ion-pair reverse-phase (IP-RP) chromatographic method has been developed for use with a time-of-flight (TOF) mass spectrometer (MS).
This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.
| Korean (Korea) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
Easy-to-use and fully integrated method for determination of DAR values for ADCs
| Korean (Korea) | Complete (PDF) |
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In this application note, we are investigating an antibody drug conjugate (ADC) with a cysteine linker.必威体育登录手机The Agilent 1290 Infinity II liquid chromatography system connected to a PLRP-S reversed phase liquid chromatography column was used to separate...
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
Using Automated Affinity Purification, LC/MS analysis, and Novel DAR Calculation Software
| Korean (Korea) | Complete (PDF) |
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Using Multiple Heart-cutting Hydrophobic Interaction/Reversed Phase 2D-LC/MS
Comparative analysis using LC-QTOF/MS between innovator and biosimilar of Rituximab
Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)
必威体育登录手机Application note for the LC/MS Walk-Up Solution from Agilent - MassHunter software
This application note describes a workflow for assessing critical quality attributes (CQAs) of intact adeno-associated viruses (AAVs), together with p...
必威体育登录手机Methods using Agilent AdvanceBio SEC columns are developed for the characterization of components of standard protein mixtures.
必威体育登录手机Describes the identification and quantitation of chemically-modified recombinant mABs with the Agilent 6545XT AdvanceBio LC/Q-TOF and Agilent MassHunt...
必威体育登录手机Software assisted prediction and identification of metabolites from biological samples using Agilent LC/Q-TOF
必威体育登录手机Methods using Agilent AdvanceBio SEC columns are developed for the characterization of components of standard protein mixtures.