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Measuring thermal-induced protein aggregation provides insight into the stability of highly concentrated mAb samples in a formulation buffer.
- Publication Part Number: 5994-4944EN
- Created: 20 July 2022
- 2 MB
This application note demonstrates the purification workflow of a single-stranded RNA ON by ion-pair reversed-phase HPLC.
- Publication Part Number: 5994-3514EN
- Created: 06 May 2021
- 365 KB
LC/MS peptide mapping approach to characterize and quantify different monoclonal antibody critical quality attributes.
- Publication Part Number: 5994-2245EN
- Created: 19 Aug 2020
- 980 KB
This application note describes a workflow for assessing critical quality attributes (CQAs) of intact adeno-associated viruses (AAVs), together with post-translational modification (PTM) identification of the capsid proteins.
- Publication Part Number: 5994-1980EN
- Created: 23 July 2020
- 791 KB
This application note describes a robust LC/MS method for the analysis of native mAb-siRNA conjugates.
- Publication Part Number: 5994-2155EN
- Created: 24 June 2020
- 3 MB
This Application Note presents an integrated workflow for peptide mapping of a mAb with Iterative MS/MS from automated sample preparation to data analysis.
- Publication Part Number: 5991-8633EN
- Created: 16 June 2020
- 2 MB
必威体育登录手机The Agilent 1220 Infinity II LC offers reliable and robust profiling and quantification for 11 of the most commonly targeted cannabinoids found in cannabis sativa.
- Publication Part Number: 5991-9285EN
- Created: 22 May 2020
- 1 MB
必威体育登录手机Meeting the requirements of the global pharmacopeias with the Agilent Cary 3500 UV-Vis
- Publication Part Number: 5994-1188EN
- Created: 27 Apr 2020
- 2 MB
Korean (Korea) | Complete (PDF) |
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Japanese (Japan) | Complete (PDF) |
Chinese (Simplified) (China) | Complete (PDF) |
This application note describes a robust LC/MS method for the analysis of native protein analysis.
- Publication Part Number: 5994-1739EN
- Created: 12 Mar 2020
- 948 KB
必威体育登录手机Comparision of innovator and bisosimilar pair using Agilent Cary 60 UV-Vis spectrophotometer
- Publication Part Number: 5991-7026EN
- Created: 17 Feb 2020
- 984 KB
Critical Quality Attribute Monitoring of mAbs at the Intact and Subunit Levels
- Publication Part Number: 5994-1349EN
- Created: 06 Dec 2019
- 611 KB
必威体育登录手机Presents a method for protein analysis using an Agilent LC/MSD XT and 1260 Infinity II LC.
- Publication Part Number: 5994-0188EN
- Created: 17 July 2019
- 249 KB
必威体育登录手机Presents a method for peptide mapping using an Agilent LC/MSD XT and 1290 Infinity II LC.
- Publication Part Number: 5994-0990EN
- Created: 26 June 2019
- 1 MB
必威体育登录手机Describes the identification and quantitation of chemically-modified recombinant mABs with the Agilent 6545XT AdvanceBio LC/Q-TOF and Agilent MassHunter BioConfirm.
- Publication Part Number: 5994-0406EN
- Created: 29 Jan 2019
- 3 MB
Japanese (Japan) | Complete (PDF) |
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An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements
- Publication Part Number: 5991-8445EN
- Created: 29 Mar 2018
- 14 MB
Chinese (Simplified) (China) | Complete (PDF) |
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This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.
- Publication Part Number: 5991-8796EN
- Created: 22 Jan 2018
- 1 MB
Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机This application note demonstrates how to increase sample throughput for glycan characterization workflows using the Agilent biopharmaceutical solution.
- Publication Part Number: 5991-8550EN
- Created: 11 Oct 2017
- 4 MB
Chinese (Simplified) (China) | Complete (PDF) |
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The application note describes a nontarget modification-specific metabolomics approach to study glycosylation modifications in various types of tea plants.
- Publication Part Number: 5991-8066EN
- Created: 19 July 2017
- 996 KB
Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机The Agilent AdvanceBio SEC column together with the Agilent 1260 Infinity II Bio-inert System is an ideal combination for the aggregate analysis of ADCs
- Publication Part Number: 5991-8244EN
- Created: 30 June 2017
- 752 KB
必威体育登录手机This application note evaluates the performance of an Agilent LC/MS in terms of achievable mass accuracy and spectral accuracy to enable unknown formula ID.
- Publication Part Number: 5991-8065EN
- Created: 19 May 2017
- 1 MB