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Aggregate analysis of adeno-associated viruses with AdvanceBio SEC 500 Å columns
- Publication Part Number: 5994-7509EN
- Created: 28 May 2024
- 729 KB
Aggregate analysis of a ~50 nm virus-like particle using an AdvanceBio SEC 1000Å column.
- Publication Part Number: 5994-7427EN
- Created: 22 May 2024
- 330 KB
In this application note, the use of the AssayMAP Bravo platform is discussed for protein analysis of antibody drug conjugate Brentuximab Vedotin in monkey plasma, with particular attention to DAR workflow development.
- Publication Part Number: 5994-7084EN
- Created: 22 Feb 2024
- 2 MB
必威体育登录手机GPC/SEC analysis of gelatin in an aqueous phosphate buffer solution using Agilent PROTEEMA columns.
- Publication Part Number: 5994-6269EN
- Created: 01 Aug 2023
- 2 MB
必威体育登录手机GPC/SEC analysis of gelatin in an aqueous phosphate buffer solution using Agilent PROTEEMA columns.
- Publication Part Number: 5994-6270EN
- Created: 01 Aug 2023
- 1 MB
必威体育登录手机GPC/SEC analysis of human insulin in water/acetic acid/acetonitrile/L-Arginin using Agilent PROTEEMA columns.
- Publication Part Number: 5994-6259EN
- Created: 01 Aug 2023
- 1 MB
The enzyme l-asparaginase poses a challenge for quantifying aggregation as its structure may produce high molecular weight aggregates.
- Publication Part Number: 5994-6587EN
- Created: 28 July 2023
- 543 KB
必威体育登录手机GPC/SEC analysis of low molecular weight heparin in an aqueous phosphate buffer solution using Agilent PROTEEMA columns according to EU pharmacopeia.
- Publication Part Number: 5994-6319EN
- Created: 01 July 2023
- 1 MB
必威体育登录手机This application brief illustrates the GPC/SEC analysis of proteins from medium to high molecular weight using an Agilent PROTEEMA column.
- Publication Part Number: 5994-5728EN
- Created: 02 Mar 2023
- 152 KB
必威体育登录手机This application brief illustrates the GPC/SEC analysis of proteins from low to medium molecular weight using an Agilent PROTEEMA column.
- Publication Part Number: 5994-5727EN
- Created: 02 Mar 2023
- 155 KB
This application brief describes the GPC/SEC analysis of monoclonal antibodies (mAb) to determine the content and size of aggregates and fragments.
- Publication Part Number: 5994-5721EN
- Created: 02 Mar 2023
- 223 KB
Aggregate and Fragment Analysis of Adeno-Associated Viral Vectors using Size Exlusion is a critical analysis.Bio SEC-5 demonstrates reproducible separation and resolution of these AAV particles and aggregates.
- Publication Part Number: 5994-4270EN
- Created: 27 Oct 2021
- 454 KB
Virus-like particles (VLPs) are highly structured protein particles that are self-assembled from one or more structural proteins, typically 20 to 150 nm in diameter.
- Publication Part Number: 5994-4227EN
- Created: 29 Sep 2021
- 194 KB
必威体育登录手机An SEC method identifying innovator and biosimilar insulin analog was developed using an Agilent AdvanceBio SEC 130Å, 7.8 × 300 mm, 2.7 μm column.
- Publication Part Number: 5991-6872EN
- Created: 12 May 2021
- 513 KB
Evaluation of SEC Columns for Analysis of ADC Aggregates and Fragments - Choosing the best stationary phase to overcome nonspecific interactions.
- Publication Part Number: 5994-3276EN
- Created: 11 May 2021
- 376 KB
必威体育登录手机This collection of 10 Agilent ‘aggregate and fragment analysis' app notes also includes our guide on how to perform SEC for biomolecule analysis.
- Publication Part Number: 5994-0032EN
- Created: 01 Apr 2021
- 7 MB
必威体育登录手机An overview of the separation and characterization of Emicizumab, using a variety of products from the Agilent biocolumns portfolio.
- Publication Part Number: 5994-2997EN
- Created: 03 Mar 2021
- 703 KB
In this application note, we have developed a mass spectrometry-compatible, native-mode size exclusion (SEC/MS) method for characterization of a challenging FDC with very low pI.
- Publication Part Number: 5994-3045EN
- Created: 09 Feb 2021
- 1 MB
Nanobody analysis with AdvanceBio SEC 120 Å 1.9 μm column for size exclusion chromatography and AdvanceBio HIC column hydrophobic interaction chromatography (HIC)
- Publication Part Number: 5994-1869EN
- Created: 15 Apr 2020
- 3 MB
Comparison of AdvanceBio SEC 200 Å 1.9 µm column for SEC analysis of hGH, hG-CSF and IFN alpha-2b therapeutic proteins with sub-2 µm particle columns from other vendors.
- Publication Part Number: 5994-1829EN
- Created: 30 Mar 2020
- 516 KB