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In this application note, the use of the AssayMAP Bravo platform is discussed for protein analysis of antibody drug conjugate Brentuximab Vedotin in monkey plasma, with particular attention to DAR workflow development.
Virus-like particles (VLPs) are highly structured protein particles that are self-assembled from one or more structural proteins, typically 20 to 150 nm in diameter.
必威体育登录手机An SEC method identifying innovator and biosimilar insulin analog was developed using an Agilent AdvanceBio SEC 130Å, 7.8 × 300 mm, 2.7 μm column.
必威体育登录手机An overview of the separation and characterization of Emicizumab, using a variety of products from the Agilent biocolumns portfolio.
In this application note, we have developed a mass spectrometry-compatible, native-mode size exclusion (SEC/MS) method for characterization of a challenging FDC with very low pI.
Comparison of HPLC method and a quick method developed using the Cary 60 UV-Vis
This application note describes a robust LC/MS method for the analysis of native protein analysis.
必威体育登录手机Size Exclusion Chromatography Method Development of NIST mAb Using an Agilent AdvanceBio SEC 200 Å, 1.9 µm Column
必威体育登录手机Describes a comparison between the Agilent AdvanceBio SEC 200 Å 1.9 µm column and other vendors' SEC columns in terms of mAb and ADC analysis.
Size exclusion chromatography with light scattering detection was used to investigate the impact of varying SDS concentration on protein molecules.
必威体育登录手机The Agilent AdvanceBio SEC column together with the Agilent 1260 Infinity II Bio-inert System is an ideal combination for the aggregate analysis of ADCs
An aggregate analysis workflow for SEC mobile phase optimization and characterization of mAb aggregation profiles
"This Application Note describes the quantification of aggregates in biotherapeutic
必威体育登录手机Agilent AdvanceBioSEC columns used for fast, high resolution, sensitive, and reproducible separation and quantitation of mAbs and Antibody Drug Conjugate,
Online 2D-LC characterization of monoclonal antibodies using SEC in the first dimension and IEX in the second dimension
必威体育登录手机A SEC method for determining the purity of PEG Granulocyte Colony Stimulating Factor using an Agilent AdvanceBio SEC column with aqueous mobile phase.
Shorter 150 mm AdvanceBio SEC columns and higher flow rates of 1.5 mL/min increase sample throughput by 400%, from 1.3 days to under 8 hours.
Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)
High resolution and sensitive size exclusion chromatography separates and quantitates rituximab aggregates/degradants in a bioinert LC with an AdvanceBio SEC column.
必威体育登录手机Methods are given for the use of Agilent Bio-SEC columns, with LS, UV and RI detection, for quantification or quality control of protein aggregates
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