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This work describes and compares two methods, Fast LC and RapidFire, for the high-throughput sampling and desalting of oligonucleotides.
| Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机This application note describes a high-throughput, ion-pairing-free method for oligonucleotide characterization using the Agilent RapidFire high-throughput MS system.
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| Chinese (Simplified) (China) | Complete (PDF) |
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RapidFire/MS/MS is capable of analyzing vitamins A and E in serum at 15 seconds/sample with comparable analytical results to LC/MS.
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Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as adverse drug-drug interactions can lead to termination of a drug development program, withdrawal from the market, or restrictions on therapeutic...
Description of an ultrafast method for performing enzyme inhibition selectivity screening using the RapidFire SPE/MS/MS system.
The RapidFire High-throughput Mass Spectrometry System provides drug discovery researchers with mass spectrometry-based...
Description of method development and optimization for cAMP measurements using the RapidFire 365 by incorporating solvent switching and multiple SPE cartridges.
必威体育登录手机Agilent's RapidFire High-throughput Mass Spectrometry system utilizes the Q-TOF MS to speed up metabolic stability data analysis by eliminating the need for MRM optimization.
必威体育登录手机A method for the ultrafast analysis of in vitro ADME samples using the Agilent RapidFire highthroughput MS system with the Agilent Ultivo triple quadrupole LC/MS for a reduced instrument footprint.
RapidFire/TOF/MS facilitates the high-throughput analysis of epigenetic modifications and repair events on DNA at 8 seconds per sample.
A modified RapidFire high throughput method that bypasses SPE desalting and enables a sub-2.5 second sample rate, making analysis of 35,000 samples a day possible
This work explores the simultaneous quantitation of a panel of nitrosamines in less than 15 seconds per injection.
During the drug discovery process, permeability assays such as Caco-2 (cell line) and PAMPA (parallel artificial membrane permeation assay) are utilized to mimic the absorption of potential drug candidates by the cells of the human intestine.
Method for analysis of six cannabinoids and their metabolites in urine using liquid chromatography with triple quadrupole mass spectrometry.
Learn about the method and results generated during the determination of asymmetric and symmetric (ADMA and SDMA) using four stream StearmSelect
RapidFire/MS/MS analysis allows for the accurate and precise measurement of a Z-drug panel in urine in under 15 seconds per sample.
RapidFire/MS/MS is capable of measuring cytochrome P450 inhibition in intact human hepatocytes at