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必威体育登录手机This Application Note shows detailed size exclusion analysis of monoclonal antibodies and their aggregates using the Agilent 1260 Infinity Multi-Detector Bio-
- Publication Part Number: 5991-3954EN
- Created: 01 May 2016
- 1 MB
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必威体育登录手机This Application Note shows the expansion of the Agilent 1260 Infinity Bio-inert Quaternary LC System with the Agilent 1260 Infinity Multi-Detector GPC/SEC System
- Publication Part Number: 5991-2884EN
- Created: 30 Apr 2015
- 1 MB
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This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
- Publication Part Number: 5991-4266EN
- Created: 01 July 2014
- 310 KB
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必威体育登录手机This Application Note shows the determination of protein molecular weightand size, together with linear quantification using the Agilent 1260 Infinity Multi-Detector Bio-SEC S
- Publication Part Number: 5991-3955EN
- Created: 01 Mar 2014
- 957 KB
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必威体育登录手机Sensitive and rapid LC methods were developed on the Agilent 1260 Bio-inert Quaternary LC system to characterize the therapeutic protein, P128.
- Publication Part Number: 5990-6192EN
- Created: 01 Dec 2013
- 819 KB
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This Application Note used hen egg white lysozyme as a model protein for purification and biophysical characterization of PEGylated proteins.
- Publication Part Number: 5991-3069EN
- Created: 01 Sep 2013
- 848 KB
Publication Part Number | 5991-3069EN | |||
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This shows the separation of four proteins by anion exchange chromatography using 4 different high salt-containing elution buffers (up to 2 M) for linear and step gradients.
- Publication Part Number: 5990-9614EN
- Created: 01 Aug 2013
- 658 KB
Publication Part Number | 5990-9614EN | |||||
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Columns containing weak cation-exchange stationary phases offer a degree of versability when used for separation of positively charged proteins.
- Publication Part Number: 5990-9628EN
- Created: 01 Aug 2013
- 1 MB
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Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机Agilent Bio MAb columns, in an Agilent 1260 Infinity Bio-inert Quaternary LC, characterize the charge heterogeneity of IgG1monoclonal antibody...
- Publication Part Number: 5991-0895EN
- Created: 01 Aug 2013
- 240 KB
Publication Part Number | 5991-0895EN | |||
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Chinese (Simplified) (China) | Complete (PDF) |
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Ion exchange is a very useful technique to separate protein mixtures under mild conditions, most commonly by applying a shallow gradient of increasing salt concentration as el
- Publication Part Number: 5990-9629EN
- Created: 01 Aug 2013
- 1 MB
Publication Part Number | 5990-9629EN | |||
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Chinese (Simplified) (China) | Complete (PDF) |
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Ion exchange is a commonly used technique for the separation of complex protein mixtures.
- Publication Part Number: 5990-9931EN
- Created: 01 Aug 2013
- 2 MB
Publication Part Number | 5990-9931EN | ||||
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Column choice in SEC depends on column resolving range, identified by calibration with standards appropriate to analyte type, molecular weight range, and size in solution.
- Publication Part Number: 5991-2463EN
- Created: 14 May 2013
- 117 KB
Publication Part Number | 5991-2463EN | ||||
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Fast and efficient LC TOF/MS characterizes intact and digested IgG to identify glycoform masses and profiles.mAb-glyco chip analysis built a glycan accurate mass database.
- Publication Part Number: 5991-2323EN
- Created: 23 Apr 2013
- 475 KB
Publication Part Number | 5990-2323EN | ||||
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Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
- Publication Part Number: 5991-2116EN
- Created: 29 Mar 2013
- 613 KB
Publication Part Number | 5991-2116EN | |||
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Chinese (Simplified) (China) | Complete (PDF) |
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This Application Note describes a simple method for the analysis of disulfide linkages in monoclonal antibodies (mAbs) by reversed phase HPLC.
- Publication Part Number: 5991-1694EN
- Created: 01 Feb 2013
- 899 KB
Publication Part Number | 5991-1694EN | ||
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Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机Methods are given for the use of Agilent Bio-SEC columns, with LS, UV and RI detection, for quantification or quality control of protein aggregates
- Publication Part Number: 5991-1400EN
- Created: 07 Jan 2013
- 284 KB
Publication Part Number | 5991-1400EN | ||||
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必威体育登录手机Agilent Captiva Premium PES syringe filters are compared with non-Agilent PES and PVDF syringe filters.
- Publication Part Number: 5991-1308EN
- Created: 26 Oct 2012
- 293 KB
Publication Part Number | 5991-1308EN | |||||
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Size exclusion chromatography (SEC) can be used for investigating the effect of temperature on a series of globular proteins to identify unfolded and/or aggregate species.
- Publication Part Number: 5990-8140EN
- Created: 10 Sep 2012
- 426 KB
Publication Part Number | 5990-8140EN | |||
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Analysis of globulins in denaturing and non-denaturing conditions using gel filtration chromatography and a ProSEC 300S column
- Publication Part Number: 5990-8141EN
- Created: 06 Sep 2012
- 425 KB
Publication Part Number | 5990-8141EN | ||||
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必威体育登录手机Rapid reversed-phase separations of intact and reduced monoclonal antibodies (mAbs) were optimized using Agilent ZORBAX RRHD 300SB-C3 columns.
- Publication Part Number: 5990-9667EN
- Created: 13 Feb 2012
- 364 KB
Publication Part Number | 5990-9667EN | |||
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Chinese (Simplified) (China) | Complete (PDF) |
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