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必威体育登录手机An SEC method identifying innovator and biosimilar insulin analog was developed using an Agilent AdvanceBio SEC 130Ã…, 7.8 × 300 mm, 2.7 μm column.
An aggregate analysis workflow for SEC mobile phase optimization and characterization of mAb aggregation profiles
"This Application Note describes the quantification of aggregates in biotherapeutic
必威体育登录手机Agilent AdvanceBioSEC columns used for fast, high resolution, sensitive, and reproducible separation and quantitation of mAbs and Antibody Drug Conjugate,
必威体育登录手机A SEC method for determining the purity of PEG Granulocyte Colony Stimulating Factor using an Agilent AdvanceBio SEC column with aqueous mobile phase.
Shorter 150 mm AdvanceBio SEC columns and higher flow rates of 1.5 mL/min increase sample throughput by 400%, from 1.3 days to under 8 hours.
Analysis of an mAb (trastuzumab) and an ADC (trastuzumab emtansine) by size exclusion chromatography with online mass spectrometry (SEC-MS)
High resolution and sensitive size exclusion chromatography separates and quantitates rituximab aggregates/degradants in a bioinert LC with an AdvanceBio SEC column.
This Application Note shows the workflow solution for the physicochemical and biological characterization of a biosimilar and innovator rituximab.
必威体育登录手机Multiple injections of Tween 20 had no effect on the performance of Agilent Bio SEC columns or integration data when analyzing IgG.
Column choice in SEC depends on column resolving range, identified by calibration with standards appropriate to analyte type, molecular weight range, and size in solution.
| Publication Part Number | 5991-2463EN | ||||
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必威体育登录手机Methods are given for the use of Agilent Bio-SEC columns, with LS, UV and RI detection, for quantification or quality control of protein aggregates
| Publication Part Number | 5991-1400EN | ||||
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必威体育登录手机Application note for the characterization of monoclonal antibodies on the Agilent 1260 Infinity Bio-inert Quaternary LC by SEC using the Agilent BioSEC columns
| Publication Part Number | 5990-6414EN | ||||
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