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Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as adverse drug-drug interactions can lead to termination of a drug development program, withdrawal from the market, or restrictions on therapeutic...
The RapidFire High-throughput Mass Spectrometry System provides drug discovery researchers with mass spectrometry-based...
This application note describes a novel 2D-LC approach using MHC and subsequent SEC desalting for native MS analysis.
必威体育登录手机Streamlined workflows for N-Glycan analysis of biotherapeutics using Agilent AdvanceBio Gly-X InstantPC and 2-AB Express sample preparation with LC/FLD/MS
必威体育登录手机Agilent's RapidFire High-throughput Mass Spectrometry system utilizes the Q-TOF MS to speed up metabolic stability data analysis by eliminating the need for MRM optimization.
RapidFire/TOF/MS facilitates the high-throughput analysis of epigenetic modifications and repair events on DNA at 8 seconds per sample.
This application note presents different approaches to native mass spectrometry.
必威体育登录手机Sensitive, high-resolution LC/MS/MS method using the Agilent 6546 LC/Q-TOF for the detection and quantification of the nitrosamine impurities
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| Japanese (Japan) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
A method describing the detection of 12 potentially mutagenic nitrosamine impurities found in sartan drugs using the Ultivo LC/TQ
| Korean (Korea) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |
| Italian (Italy) | Complete (PDF) |
This Application Note describes a routine analysis workflow for pharmaceutical QA/QC labs.
| Korean (Korea) | Complete (PDF) |
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This application note describes a robust LC/MS method for the analysis of native mAb-siRNA conjugates.
This application note describes a robust LC/MS method for the analysis of native protein analysis.
A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
必威体育登录手机Describes a workflow for monitoring multiple mAb characteristics involving the Agilent 1290 Infinity II 2D-LC System.
必威体育登录手机This application note describes an LC/MS/MS method using the Agilent 6470A triple quadrupole LC/MS for the detection and quantification of NDMA in ranitidine drug substances and products.
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
必威体育登录手机This application note presents the use of the Agilent 6560 ion mobility LC/Q-TOF to analyze the formation of multimers of bovine serum albumin (BSA) in various mobile phases.
必威体育赛事投注This application note describes a sensitive, high-resolution LC/MS/MS method using the 6546 LC/Q-TOF for the detection and quantification of NDMA in ranitidine drug substance and products.
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
| Japanese (Japan) | Complete (PDF) |
必威体育赛事投注The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
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| Chinese (Simplified) (China) | Complete (PDF) |
Critical Quality Attribute Monitoring of mAbs at the Intact and Subunit Levels
An automated workflow for the analysis of protein phosphorylation from sample preparation with phosphopeptide enrichment to analysis by IMS.