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In this application note, the use of the AssayMAP Bravo platform is discussed for protein analysis of antibody drug conjugate Brentuximab Vedotin in monkey plasma, with particular attention to DAR workflow development.
Comparison of AdvanceBio SEC 200 Å 1.9 µm column for SEC analysis of hGH, hG-CSF and IFN alpha-2b therapeutic proteins with sub-2 µm particle columns from other vendors.
Improvements in resolution and shorter run times using AdvanceBio SEC 120 Å 1.9 μm, 4.6 x 300 mm column for insulin analysis.
An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements
Combining HILIC with MS for the analysis of underivatized amino acids in fermentation media.
必威体育登录手机This application note demonstrates how to increase sample throughput for glycan characterization workflows using the Agilent biopharmaceutical solution.
Demonstion of the use of multiple heart-cutting two-dimensional liquid chromatography for automated desalting of glucagon from an MS incompatible USP method.
This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.
必威体育登录手机Small –scale purification of a monoclonal antibody from a cell lysate and the subsequent analysis on a single instrument, the Agilent 1260 Infinity Bio-inert Quaternary LC.
| Publication Part Number | 5991-1195EN | ||||
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Using Multiple Heart-cutting Hydrophobic Interaction/Reversed Phase 2D-LC/MS
必威体育登录手机This Application note demonstrates peptide mapping of a therapeutic mAb using Agilent 1260 Bio-inert Quaternary LC with fusion QbD method development software.
Biomolecule Characterization workflow.必威体育登录手机Agilent Bio-Monolith Protein A and G Affinity columns.and 1260 Infinity Bio-Inert LC System.
必威体育登录手机Now you have more columns and more choices to improve your charged-variant analysis of proteins with the Agilent Ion-exchange BioHPLC columns.
必威体育登录手机Resolve mAbs faster and better with Agilent AdvanceBio RP-mAb columns.
必威体育登录手机Agilent's range of preparative particle size columns and phases are designed for high loadability.
Ion exchange is a commonly used technique for the separation of complex protein mixtures.
| Publication Part Number | 5990-9931EN | ||||
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Ion exchange is a very useful technique to separate protein mixtures under mild conditions, most commonly by applying a shallow gradient of increasing salt concentration as el
| Publication Part Number | 5990-9629EN | |||
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This shows the separation of four proteins by anion exchange chromatography using 4 different high salt-containing elution buffers (up to 2 M) for linear and step gradients.
| Publication Part Number | 5990-9614EN | |||||
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必威体育登录手机This Application Note describes a high-resolution, pH-based separation of acidic and basic charge variants for monoclonal antibodies using the Agilent 1260 and BiomAb PEEK
| Publication Part Number | 5991-1407EN | ||
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必威体育登录手机Rapid reversed-phase separations of intact and reduced monoclonal antibodies (mAbs) were optimized using Agilent ZORBAX RRHD 300SB-C3 columns.
| Publication Part Number | 5990-9667EN | |||
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