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From Classical to Online Monitoring of G-Protein-Coupled Receptor Stimulation in Living Cells (PDF)

To determine if the stimulation of endogenously expressed GPCRs can be monitored by the xCELLigence system, cells were stimulated with various receptor agonists, triggering either Gs-, Gi-, or Gq-mediated downstream signals.

  • Publication Part Number: 5994-1940EN
  • Created: 02 Feb 2021
  • 3 MB
  • PDF
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Enhancing Immune Cell Cytotoxicity and Persistence Insights Using Real-Time Cell Analysis (PDF)

This editorial will discuss the potency assays available for cellular immunotherapies, the regulatory criteria they must meet, and the challenges faced in measuring immune cell cytotoxicity.

  • Publication Part Number: 5994-7162EN
  • Created: 15 Feb 2024
  • 1 MB
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The Role of Potency Assays in Cell Therapy Manufacturing (PDF)

Although cell therapies have shown great promise in clinical studies, challenges with the large scale manufacturing of these therapies still need to be addressed.

  • Publication Part Number: 5994-4702EN
  • Created: 17 Aug 2022
  • 721 KB
  • PDF
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Case Study: Tmunity Therapeutics - Building a CAR-T Toolbox for More Comprehensive Assessment of Cell Therapies (PDF)

Dr.Daniel Hui from Tmunity Therapeutics addresses challenges with cell therapy development with an innovative CAR-T toolbox, using xCELLigence RTCA for measuring potency of immune cell therapies.

  • Publication Part Number: 5994-4469EN
  • Created: 26 Jan 2022
  • 395 KB
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