Bio IEX Ion Exchange Chromatography Columns
PL-SAX for Biomolecules
PL-SAX for Biomolecules delivers improved chromatography for self-complementary or G-rich sequences that may associate to form aggregates or hairpin structures.The 5 μm material provides high-efficiency separations of n and n-1 sequences, with 8 μm, 10 μm, and 30 μm particles available for rapid scale-up.
- Oligonucleotide Analysis Columns and Standards
Product Details
- Small particles deliver excellent chromatographic performance
- Wide range of particle sizes for flexible oligonucleotide analysis and scale-up purification
- Exceptional stability for long column lifetime
- Need help?Try our Bio HPLC Column Selector Tools.
Bio HPLC Columns eSelector Tools
Intuitive process to help you select the right chromatography column for your biopharmaceutical applications.
Preparative HPLC Scaling Calculator
Scale between analytical and prep methods!calculate column capacity, # of injections, run time & mobile phase use.
Oligonucleotide Virtual Lab
Explore proven methods and resources to help advance analysis for the broad range of oligonucleotide workflows.
Videos
- Key Literature
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Optimizing Separation of Oligonucleotides with Anion-Exchange Chromatography
This application note describes common method parameters that can be optimized when purifying oligonucleotides ranging from 25 to 100 bases in length.
- Application Notes
- English
- 11 Apr 2022
- 416.32 KB
必威体育登录手机Oligonucleotide Purification Solutions - Agilent PLRP-S and PL-SAX HPLC Columns
Polymeric particles, such as PLRP-S and PL-SAX, are ideal for analyzing and purifying oligonucleotides.Because these materials are thermally and chemically stable, they enable diverse techniques.
- Brochures
- English
- 20 Oct 2023
- 4.15 MB
Oligonucleotide Purification using Anion Exchange Liquid Chromatography
Easily find all you need for oligonucleotide purification using anion exchange liquid chromatography with this workflow ordering guide.
- Brochures
- English
- 23 Apr 2024
- 623.89 KB
- Application Notes
- Catalogs
- Posters
- Technical Overviews
- FAQs
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Bio LC Column User Guides
User guides contain helpful information to ensure the best performance from your column, such as operating parameters, cleaning and storage guidelines, usage tips, and suggested starting conditions.
- User Manuals
Semi-Preparative Purification of Synthetic Oligonucleotides
This application note discusses the optimum conditions for purification of a synthetic oligonucleotide and scaling up to a 10 mm internal diameter column using the same analytical HPLC instrument.The latest developments include columns packed with superficially porous particles that provide excellent performance and resolution without compromising column loading.
- 03 Jun 2024