xCELLigence RTCA ePacer - Cardiomyocyte Pacing
- RTCA Analyzers
Product Details
- Improve cell maturation status in 2-3 weeks
- Enable precise control of the beating rate over different time durations
- Improve cardiomyocyte response to inotropic compounds and sarcomeric structure.
- Scalable system allows you to pace your cells from just a few wells up to six 48- or 96- well E-Plates.
- Compatible with calcium measurements, high content microscopy, voltage sensitive dyes, plate readers, etc.
- Application Notes
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必威体育登录手机Cardiotoxicity Assessment of Antiviral Drugs Using the Agilent xCELLigence RTCA CardioECR System
必威体育登录手机This study used the Agilent xCELLigence RTCA CardioECR system with human iPSC-derived cardiomyocytes (hiPSC-CMs) to evaluate cardiac safety/toxicity of antiviral drugs.
- Application Notes
- English
- 21 May 2024
- 1.55 MB
Multimodal Connected Workflow for Cardiotoxicity Assessment Using Human iPSC-Derived Cardiomyocytes
必威体育登录手机This application note demonstrates the feasibility and use of combining multiple cell-based in vitro assays from Agilent that use diverse analytical technologies to investigate the cardiac liability of drugs.
- Application Notes
- English
- 26 Sep 2022
- 1002.14 KB
Connected Workflow: Assessment of Inotropic Compounds in PacedCardiomyocytes Using Calcium Imaging
This app note demonstrates the feasibility of using a connected workflow to evaluate the effect of inotropic compounds on electrically paced human iPSC derived cardiomyocytes (hiPSC-CMs) through calcium imaging
- Application Notes
- English
- 06 Jun 2022
- 2.93 MB
必威体育登录手机Assessment of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Disease Models Using the Agilent xCELLigence CardioECR System
必威体育登录手机A demonstration of the use of the Agilent xCELLigence RTCA CardioECR system to compare functional profiles of contractility and electrophysiology between an PS-iPSC-CM disease model and its isogenic control.
- Application Notes
- English
- 10 Sep 2021
- 2.82 MB
必威体育登录手机Using the Agilent xCELLigence RTCA ePacer for Functional Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
必威体育登录手机This application note presents a method for improving human-induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) maturation using the Agilent xCELLigence RTCA ePacer system.
- Application Notes
- English
- 11 Feb 2021
- 5.39 MB
A Real-Time Impedance Analysis Instrument for Cardiac Safety and Toxicity Assessment
In this application note, the RTCA Cardio instrument is used with human stem cell-derived cardiomyocytes (iCell Cardiomyocytes) for assessment of the cardiac safety profile of leading compounds or drug candidates during drug development.
- Application Notes
- English
- 04 Dec 2020
- 2.01 MB
必威体育登录手机The Agilent xCELLigence RTCA CardioECR System: A Multiparametric Functional Analysis Instrument for Cardiac Safety and Toxicity Assessment
In this application note, we used the xCELLigence RTCA CardioECR system (CardioECR system) in conjunction with hiPS-CMs for the assessment of preclinical cardiac risks.
- Application Notes
- English
- 16 Jul 2020
- 4.82 MB
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