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IQFISH Panel for Lymphoma (Manual)

The IQFISH manual panel for lymphoma is intended for the detection of rearrangements involving the MYC, BCL2, BCL6, CCND1, MALT1 and IGH genes by FISH on lymph node FFPE tissue sections.

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IQFISH Panel for Lung Cancer

Dako Omnis, a fully automated, walk-away solution for advanced staining, provides a flexible and efficient FISH solution.With the short FISH protocol and high slide and reagent capacity, Dako Omnis processes FISH slides in an IHC-like turnaround...

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IQFISH Panel for Lung Cancer (Manual)

The IQFISH manual panel for lung cancer is intended for the detection of rearrangements involving the ALK, ROS1 and RET genes, and the detection of MET gene amplification by FISH on lung FFPE tissue sections.

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IQFISH Panels

The IQFISH panels include a set of oligonucleotide-based ready-to-use FISH probes, premixed with IQFISH hybridization buffer, for the detection of gene rearrangements and for the detection of gene amplifications by fluorescence in situ hybridization...

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HER2 IQFISH pharmDx

The human HER2 gene with the generic name ERBB2 (also known as NEU) encodes the HER2 protein or p185HER2.The HER2 protein is a membrane receptor tyrosine kinase with homology to the epidermal growth factor receptor (EGFR).The HER2 gene is a normal...

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IQFISH Fast Hybridization Buffer

IQFISH fast hybridization buffer is a formamide-free hybridization buffer that enables hybridization to be completed in 1-1.5 hours.IQFISH buffer is provided in three different size formats to meet the needs of varying testing volumes.

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IQFISH Fast Hybridization Buffer is a formamide-free hybridization buffer that enables ISH hybridization to be completed in 1-1.5 hours.A complete in situ hybridization (ISH) assay on a formalin-fixed, paraffin-embedded (FFPE) sample can be completed in 4 hours enabling a half day sample-to-result workflow.This workflow offers many operation advantages such as increased turnaround time, same day repeat testing without impacting the quality of hybridization.|Standard formamide-based FISH hybridization buffer lowers the melting temperature of nucleic acids by targeting hydrogen bonds and interfering with DNA base pairing resulting in the denaturation of the DNA double strand.The interference slows down the following base pairing between the FISH probe and specimen DNA.However, IQFISH buffer destabilizes the DNA helix by diminishing hydrophobic base stacking (1).Minimized based paring interference enables fast binding between the ISH probe and specimen DNA.|IQFISH buffer is provided in three different size formats to meet the needs of varying testing volumes.
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MET IQFISH Probe with CEP7 (Dako Omnis)

MET IQFISH Probe with CEP7 (Dako Omnis) is intended for the detection of the MET gene amplification by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded...

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MET IQFISH Probe with CEP7 (Dako Omnis) is intended for the detection of the MET gene amplification by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.|In normal diploid cells in metaphase or interphase, the MET IQFISH Probe with CEP7 generates two orange-red signals (MET) and two green signals (chromosome 7).In cells with a gain or amplification of the MET gene or of chromosome 7, the number of signals per cell will be greater.
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MET IQFISH Probe with CEP7

The MET IQFISH Probe with CEP7 is intended for the detection of MET gene amplification by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.

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The MET IQFISH Probe with CEP7 is intended for the detection of MET gene amplification by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.|In normal diploid cells in metaphase or interphase, the MET IQFISH Probe with CEP7 generates two orange-red signals (MET) and two green signals (chromosome 7).In cells with a gain or amplification of the MET gene or of chromosome 7, the number of signals will be greater.
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ROS1 IQFISH Break-Apart Probe (Dako Omnis)

ROS1 IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ROS1 gene by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed,...

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ROS1 IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ROS1 gene by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.|Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation breakpoint for a given gene, each labeled with a different fluorochrome.These probes generate signals in normal cells that are closely matched in size and co-localized (two fusion signals).In case of a translocation event, the signals are 'broken apart' and no longer co-localize giving e.g.one red, one green and one fusion signal.
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ROS1 IQFISH Break-Apart Probe

The ROS1 IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the ROS1 gene by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.

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The ROS1 IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the ROS1 gene by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.|Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation break point for a given gene, each labeled in a different color.These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion).Following a translocation, the signals are 'broken apart' and no longer co-localize (for example: 1 red, 1 green, 1 fusion).
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BCL2 IQFISH Break-Apart Probe

BCL2 IQFISH Break-Apart Probe labeled with Cy3 and FITC is intended for the detection of translocations involving the BCL2 gene by fluorescence in situ hybridization (FISH) and may result in 1 orange-red, 1 green, 1 fusion signal.The probe is to be...

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BCL2 IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the BCL2 gene by fluorescence in situ hybridization (FISH).The probe is to be used on formalin-fixed, paraffin-embedded tissue sections.|Break apart probes consist of two child probes (3' and 5' probes), designed to hybridize on opposite sides of the translocation break point for a given gene, each labeled in a different color (Cy3 and FITC).These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion signals).Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).|BCL2 IQFISH Break-Apart Probe and corresponding protocol were developed using formalin-fixed, paraffin-embedded, lymph node tissue sections.|Child Probe 5' RD, Chr18!Start 61043686, Stop 61641631|Child Probe 3' GR, Chr18!Start 60140026, Stop 60763791
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CCND1 IQFISH Break-Apart Probe

CCND1 IQFISH Break-Apart Probe labeled with Cy3 and FITC is intended for the detection of translocations involving the CCND1 gene by fluorescence in situ hybridization (FISH) and may result in 1 orange-red, 1 green, 1 fusion signal.The probe is to...

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CCND1 IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the CCND1 gene by fluorescence in situ hybridization (FISH).The probe is to be used on formalin-fixed, paraffin-embedded tissue sections.|Break apart probes consist of two child probes (3' and 5' probes), designed to hybridize on opposite sides of the translocation break point for a given gene, each labeled in a different color (Cy3 and FITC).These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion signals).Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).|CCND1 IQFISH Break-Apart Probe and corresponding protocol were developed using formalin-fixed, paraffin-embedded, lymph node tissue sections.|Child Probe 5' RD, Chr11|Start 68407510, Stop 68718885|Child Probe 3' GR, Chr11|Start 69365371, Stop 69717561
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RET IQFISH Break-Apart Probe (Dako Omnis)

RET IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the RET gene by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed,...

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RET IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the RET gene by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.|Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation breakpoint for a given gene, each labeled with a different fluorochrome.These probes generate signals in normal cells that are closely matched in size and co-localized (two fusion signals).In case of a translocation event, the signals are 'broken apart' and no longer co-localize giving e.g.one red, one green and one fusion signal.
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RET IQFISH Break-Apart Probe

The RET IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the RET gene by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.

Break-apart probes...

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The RET IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the RET gene by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.|Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation break point for a given gene, each labeled in a different color.These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion).Following a translocation, the signals are 'broken apart' and no longer co-localize (for example: 1 red, 1 green, 1 fusion).
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ALK IQFISH Break-Apart Probe (Dako Omnis)

ALK IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed,...

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ALK IQFISH Break-Apart Probe (Dako Omnis) is intended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH).The dual-color probe for Dako Omnis is recommended to be used on formalin-fixed, paraffin-embedded (FFPE) lung tissue specimens.|Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation breakpoint for a given gene, each labeled with a different fluorochrome.These probes generate signals in normal cells that are closely matched in size and co-localized (two fusion signals).In case of a translocation event, the signals are 'broken apart' and no longer co-localize giving e.g.one red, one green and one fusion signal.
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ALK IQFISH Break-Apart Probe

The ALK IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.

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The ALK IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the ALK gene by fluorescence in situ hybridization (FISH).The probe is to be used on lung paraffin-embedded tissue sections.|Break-apart probes consist of two child probes, designed to be on opposite sides of the translocation break point for a given gene, each labeled in a different color.These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion).Following a translocation, the signals are 'broken apart' and no longer co-localize (for example: 1 red, 1 green, 1 fusion).
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BCL6 IQFISH Break-Apart Probe

BCL6 IQFISH Break-Apart Probe labeled with Cy3 and FITC is intended for the detection of translocations involving the BCL6 gene by fluorescence in situ hybridization (FISH) and may result in 1 orange-red, 1 green, 1 fusion signal.The probe is to be...

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BCL6 IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the BCL6 gene by fluorescence in situ hybridization (FISH).The probe is to be used on formalin-fixed, paraffin-embedded tissue sections.|Break apart probes consist of two child probes (3' and 5' probes), designed to hybridize on opposite sides of the translocation break point for a given gene, each labeled in a different color (Cy3 and FITC).These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion signals).Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).|BCL6 IQFISH Break-Apart Probe and corresponding protocol were developed using formalin-fixed, paraffin-embedded, lymph node tissue sections.|Child Probe 5' GR, Chr3|Start 187735129, Stop 188216099|Child Probe 3' RD, Chr3|Start 187067109, Stop 187438594
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MYC IQFISH Break-Apart Probe

MYC IQFISH Break-Apart Probe labeled with Cy3 and FITC is intended for the detection of translocations involving the MYC gene by fluorescence in situ hybridization (FISH) and may result in 1 orange-red, 1 green, 1 fusion signal.The probe is to be...

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MYC IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the MYC gene by fluorescence in situ hybridization (FISH).The probe is to be used on formalin-fixed, paraffin-embedded tissue sections.|Break apart probes consist of two child probes (3' and 5' probes), designed to hybridize on opposite sides of the translocation break point for a given gene, each labeled in a different color (Cy3 and FITC).These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion signals).Following a translocation, the signals are "broken apart" and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).|MYC IQFISH Break-Apart Probe and corresponding protocol were developed using formalin-fixed, paraffin-embedded, lymph node tissue sections.|Child Probe 5' RD, Chr8|Start 127977211, Stop 128481671|Child Probe 3' GR, Chr8|Start 130342021, Stop 130739576
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MALT1 IQFISH Break-Apart Probe

MALT1 IQFISH Break-Apart Probe labeled with Cy3 and FITC is intended for the detection of translocations involving the MALT1 gene by fluorescence in situ hybridization (FISH) and may result in 1 orange-red, 1 green, 1 fusion signal.The probe is to...

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MALT1 IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the MALT1 gene by fluorescence in situ hybridization (FISH).The probe is to be used on formalin-fixed, paraffin-embedded tissue sections.|Break apart probes consist of two child probes (3' and 5' probes), designed to hybridize on opposite sides of the translocation break point for a given gene, each labeled in a different color (Cy3 and FITC).These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion signals).Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).|MALT1 IQFISH Break-Apart Probe and corresponding protocol were developed using formalin-fixed, paraffin-embedded, lymph node tissue sections.|Child Probe 5' RD, Chr18|Start 56037816, Stop 56337411|Child Probe 3' GR, Chr18|Start 56421006, Stop 57023901
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IGH IQFISH Break-Apart Probe

IGH IQFISH Break-Apart Probe labeled with Cy3 and FITC is intended for the detection of translocations involving the IGH gene by fluorescence in situ hybridization (FISH) and may result in 1 orange-red, 1 green, 1 fusion signal.The probe is to be...

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IGH IQFISH Break-Apart Probe is intended for the detection of rearrangements involving the IGH gene by fluorescence in situ hybridization (FISH).The probe is to be used on formalin-fixed, paraffin-embedded tissue sections.|Break apart probes consist of two child probes (3' and 5' probes), designed to hybridize on opposite sides of the translocation break point for a given gene, each labeled in a different color (Cy3 and FITC).These probes generate signals in normal cells that are closely matched in size and co-localized (2 fusion signals).Following a translocation, the signals are “broken apart” and no longer co-localize (for example: 1 orange-red, 1 green, 1 fusion).|IGH IQFISH Break-Apart Probe and corresponding protocol were developed using formalin-fixed, paraffin-embedded, lymph node tissue sections.|Child Probe 5' GR, Chr14|Start 106651040, Stop 107288785|Child Probe 3' RD, Chr14|Start 105770335, Stop 106069355
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