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81 - 100 of 260 results
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An automated precolumn OPA/FMOC amino acid method for 3.5 and 1.8 µm ZORBAX Eclipse Plus C18 transfers to 2.7 µm Poroshell HPH-C18 with good lifetime and results
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Method development for impurity analysis using multiple heart-cutting 2D-LC
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| Korean (Korea) | Complete (PDF) |
| Japanese (Japan) | Complete (PDF) |
OligoPore resolves oligomers of oligopin and vitaflavan better than individual pore size columns
| Publication Part Number | 5991-0487EN | |||||
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This Application Note demonstrates the utility of capillary electrophoresis/mass spectrometry (CE/MS) for the analysis of intact monoclonal antibodies.
必威体育登录手机Agilent Bio-Monolith Protein A delivers high-throughput, precise, accurate, linear, and robust separation of mAbs to optimize clone selection and cell cultures.
必威体育登录手机A versatile Agilent Bio-Monolith Protein A column analyzed an optimized recombinant mAb manufactured with desired structural characteristics.
必威体育登录手机An Agilent Bio-Monolith Protein A column determined recombinant mAb titer and was used to enrich µg amounts of antibody for further structural characterization by MS.
必威体育登录手机An Agilent 2.7 µm HILIC column revealed a glycopeptide not seen by RP.HILIC can be orthogonal and complementary to RP for better retention of hydrophilic peptides.
Two application kits have been developed to assess the efficiency and reproducibility of MRM-based peptide quantitation.
This Application Note shows the workflow solution for the physicochemical and biological characterization of a biosimilar and innovator rituximab.
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
| Publication Part Number | 5991-4266EN | ||
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必威体育登录手机The Agilent HILIC-based AdvanceBio Glycan Mapping column is 40% faster, with high resolution, efficiency, and chemical stability for at least 5,000 column volumes.
| Chinese (Simplified) (China) | Complete (PDF) |
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必威体育登录手机The Agilent 1.8 µm HILIC column reduced run time by 40% when separating N-linked glycans.The column also resolved complex antennary bovine fetuin glycans.
The sensitivity of UHPLC/MS method on an 6150 Series Single Quadrupole LC/MS was demonstrated for the application of cleaning verification studies of highly potent drugs.
| Publication Part Number | 5991-4509EN | |||
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必威体育登录手机This Application Note describes the quantification of human IgG with the Agilent Bio-Monolith Protein A HPLC Column with alternating column regeneration.
| Publication Part Number | 5991-4723EN | ||
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Antibody conjugates are of significant interest in biopharma industry as therapeutic agents.This note demonstrates the use of the CE/MS analysis for immunoconjugates.
An "addition only" tryptic protein-digestion protocol, followed by multiplexed SISCAPA peptide enrichment, was developed and automated in 96-well format
This Application Note describes the performance of a detector
Application note for low temperature spectroscopy of a reaction center mutant of Rhodobacter sphaeroidies